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Pancreatic Alpha-Cell Dysfunction Contributes to the Disruption of Glucose Homeostasis and Compensatory Insulin Hypersecretion in Glucocorticoid-Treated Rats

Figure 3

The pancreatic α-cell mass in DEX rats.

A: Panoramic and detailed view of DEX and CTL pancreas sections that were immunostained for glucagon. B: Relative, C: absolute, and D: normalized α-cell mass in DEX and CTL rats. Data are the mean ± SEM (n = 6). Scale bars = 200, 50, 20 and 10 µm from the top to bottom images in A.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0093531.g003