Polymerase I and Transcript Release Factor Acts As an Essential Modulator of Glioblastoma Chemoresistance
Figure 6
The cell viability (IC50) changes after PTRF konckdown.
(A) The cell viabilty of U251AR cells, U251AR cells transfected with shNC and U251AR cells transfected with shPTRF after treatment with 100 µg/mL TMZ for 24 h, 48 h, 72 h, 96 h, and 120 h; (B) The IC50 of U251AR cells and U251AR cells transfected with shNC and shPTRF; (C) The IC50 of U251 cells and U251 cells transfected with shNC and shPTRF. **, P<0.05.