Radiotherapy-Induced Anti-Tumor Immunity Contributes to the Therapeutic Efficacy of Irradiation and Can Be Augmented by CTLA-4 Blockade in a Mouse Model
Figure 2
Effect of X-ray irradiation on EL4 tumors in BALB/c-nu/nu mice.
(A) Growth curves of EL4 tumors in the irradiated group (n = 5). X-ray irradiation was performed on Day 10; bars, SD. (B) Survival curves for EL4-inoculated BALB/c-nu/nu mice. (C) Systemic metastases (arrows) in the internal organs of a representative mouse 20 days after tumor inoculation.