High and Low Doses of Ionizing Radiation Induce Different Secretome Profiles in a Human Skin Model
Figure 2
Trends associated with protein abundance profiles and doses of ionizing radiation.
Protein abundance fold change at each radiation dose was normalized to that of sham (0 cGy) using log2 ratio and plotted as the y axis. Each line represents profile of one protein with increasing doses of ionizing radiation along the x axis. A) 97 proteins with their abundances decreased; B) 9 proteins with their abundances increased; C) 21 proteins with their abundances highest at 10 cGy; D) 8 proteins with their abundances lowest at 10 cGy. Detailed statistical analysis values, such as fold change and p values from Dunnett adjusted 2-sided t-test are listed in Supporting Information Table S1.