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High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of the Bone Marrow Niche

Figure 1

High Fat Diet Induces an Obese Phenotype.

(a,b) At 6 weeks HF animals have expanded total abdominal adiposity with a prominent shift in the location of this adiposity from primarily subcutaneous to the visceral compartment. (c) The expansion and relocation of adiposity is illustrated in 3D reconstructions of abdominal μCT images which have been thresholded for adiposity (n = 9). In these images gray represents subcutaneous fat and pink represents visceral fat. *P<0.05 vs. RD.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0090639.g001