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Anti-Inflammatory and Anti-Remodelling Effects of ISU201, a Modified Form of the Extracellular Domain of Human BST2, in Experimental Models of Asthma: Association with Inhibition of Histone Acetylation

Figure 6

Relative expression of mRNA for IL-13 by primed CD4+ T cells co-cultured with MH-S cells.

Cells were either untreated or stimulated with IL-33 in the absence or presence of ISU201 or dexamethasone. Data are mean ± SEM (n = 3 samples per group). Significant differences relative to unstimulated cells are shown as *** (p<0.001); relative to IL-33-stimulated cells in medium alone are shown as ##(p<0.01) and ###(p<0.001).

Figure 6

doi: https://doi.org/10.1371/journal.pone.0090436.g006