Hypothermic Oxygenated Machine Perfusion Prevents Arteriolonecrosis of the Peribiliary Plexus in Pig Livers Donated after Circulatory Death
Figure 3
Comparison of biochemical parameters of bile duct injury and oxidative stress in DCD livers that were preserved by either 4 h of oxygenated HMP or 4 h of SCS and subsequently reperfused for 2 h by normothermic ex vivo sanguineous perfusion.
Panel A–C: Concentration of LDH, alkaline phosphatase, and gamma-GT in bile samples at 2 h after reperfusion. Panel D: Comparison of biliary concentration of TBARS, a marker for oxidative stress and lipid peroxidation in bile ducts, at 2 h after graft reperfusion. There were no significant differences between the SCS preserved and HMP preserved livers.