Ginsenoside Metabolite Compound K Promotes Recovery of Dextran Sulfate Sodium-Induced Colitis and Inhibits Inflammatory Responses by Suppressing NF-κB Activation
Figure 4
CK reduces production of inflammatory cytokines in DSS-induced colitis in mice.
The colon tissues and mice serum were collected as the mean shows in method and materials. Before it performed, the tissues were fixed with ice-cold PBS in 1∶9 rations, homogenated, and centrifugalized. The supernatants were collected and IL-1β, TNF-α, IL-6 and IL-10 expressions were measured by ELISA (n = 3). The results were shown in (A), (B), (C) and (D), respectively. (E) and (F) The mice serum is detected the production of IL-1β, IL-6 directly by ELISA (n = 3). # p<0.05, ## p<0.01, ### p<0.01 compared with the control group. *p compared with DSS4D3DR or DSS7D3DR group. *p<0.05, **p<0.01, ***p<0.01.