Cortical Dysfunction Underlies the Development of the Split-Hand in Amyotrophic Lateral Sclerosis
Figure 5
The cortical silent period (CSP) is a biomarker of cortical inhibitory circuit function.
The CSP duration was significantly reduced when recording when recording over the (A) abductor pollicis brevis (APB) and (B) first dorsal interosseous (FDI) muscles. (C) There was no significant (NS) reduction in CSP duration when recording over the abductor digit minimi (ADM) muscle.