The Monocyte to Macrophage Transition in the Murine Sterile Wound
Figure 2
Surface marker expression on day 1 and day 14 wound macrophage subsets.
C57BL/6J mice were wounded for 1 or 14 days, and the surface expression of MHC class II, CD11c and CD206 on wound monocyte/macrophage subsets was determined by flow cytometry. Wound monocyte/macrophage subsets were defined as F4/80+Ly6Chi (Ly6Chi) and F4/80+Ly6Clow (Ly6Clow). Mean fluorescence intensities (MFI; geometric mean) were calculated and are presented as the mean ± SD, n = 4 mice per group. Data are representative of at least 3 independent experiments.