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A Novel In Vivo Vascular Imaging Approach for Hierarchical Quantification of Vasculature Using Contrast Enhanced Micro-Computed Tomography

Figure 3

Robustness results for densitometric analysis of the lower hind limb.

Average X-ray absorption values in blood (A) and muscle (B) when 0%, 50% and 100% of the standard contrast volume were injected. Significant differences were found between all three cases. C) Vascular density values calculated with the densitometric analysis corresponding to 50% and 100% of the standard contrast volume. No significant differences were found for vascular density, which indicated that it is not influenced by the injected dose of contrast agent. ***p<0.001, **p<0.01. N = 7/group.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0086562.g003