A1M/α1-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia
Figure 5
Placenta histology visualized by light microscopy.
The histology of placenta was assessed in light microscopy of HE-stained slides. A. HE-stained placentome of a healthy control ewe at gestation d135 (2× magnification). The hilar zone is marked (HZ) and the square show the haemophagus area where differences were observed. B. HE stained haemophagus area of the placentome from a representative control ewe (10× magnification). C. HE stained haemophagus area of the placentome from a representative starved placebo ewe (10× magnification). Areas with increased erythrophagocytosis are marked with arrows. D. HE stained haemophagus area of the placentome from a representative starved A1M-treated ewe. Note the decreased amount of erythrocyte debris.