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Combined Therapy of Iron Chelator and Antioxidant Completely Restores Brain Dysfunction Induced by Iron Toxicity

Figure 3

Effects of iron overload on brain mitochondrial function.

Each panel represented brain mitochondrial ROS production (A), brain mitochondrial membrane potential changes (B) and brain mitochondrial swelling (C). *P<0.05 vs. Normal diet groups; P<0.05 vs. HFe4w. ND: normal diet fed groups; HFe: high-iron diet fed groups.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0085115.g003