HCV Genomic RNA Activates the NLRP3 Inflammasome in Human Myeloid Cells
Figure 2
HCV virion treatment does not trigger IL-1β secretion in human myeloid cells.
THP-1 cells (A), THP-1 derived macrophages (B), human primary monocytes (C), human primary unprimed (D) and LPS primed (E) macrophages were treated with purified HCV virions at different MOI for 12 hours and the supernatants were harvested for IL-1β ELISA testing. Data shown here represent the mean ± SD of at least three independent experiments performed with internal triplicates.