Phenotyping of Human Melanoma Cells Reveals a Unique Composition of Receptor Targets and a Subpopulation Co-Expressing ErbB4, EPO-R and NGF-R
Figure 2
Expression of KIT/CD117 on human melanocytes.
Normal epidermal foreskin melanocytes were stained with fluorochrome-conjugated monoclonal antibodies (mAb) directed against CD31, CD45 and CD146 for melanocyte detection, and mAb against KIT and EPO-R. Specificity of the staining reaction was controlled by applying an isotype-matched IgG2b antibody (left panel). As visible, melanocytes expressed KIT but did not express substantial amounts of EPO-R.