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Histopathological Analysis of Salmonella Chronic Carriage in the Mouse Hepatopancreatobiliary System

Figure 3

Salmonella LPS staining was detected in the liver regardless of the presence of gallstones.

Representative IHC images of mouse liver sections at 3 and 9 months post-infection using an anti-Salmonella LPS antibody. Panel C shows a typhoid nodule. Black arrows indicate the presence of Salmonella inside inflammatory macrophages (Panel C) or Kupffer cells (Panel F) or intracellularly in hepatocytes (Panels D, E). DAB and hematoxylin counterstain. 40x.

Figure 3

doi: https://doi.org/10.1371/journal.pone.0084058.g003