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A Metabolomic Analysis of Omega-3 Fatty Acid-Mediated Attenuation of Western Diet-Induced Nonalcoholic Steatohepatitis in LDLR-/- Mice

Figure 7

Diet effects on hepatic one-carbon, choline and glutathione metabolism.

Panel A: Pathways for one-carbon, choline, glutathione and sphingomyelin metabolism. Panel B: Metabolites quantified by the metabolomic analysis were expressed as Metabolite-Fold Change and represented as mean ± SD, n=8 per group; *, p ≤ 0.05 versus chow; #, p ≤ 0.05 versus WD + O.

Figure 7

doi: https://doi.org/10.1371/journal.pone.0083756.g007