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Impact of Perinatal Systemic Hypoxic–Ischemic Injury on the Brain of Male Offspring Rats: An Improved Model of Neonatal Hypoxic–Ischemic Encephalopathy in Early Preterm Newborns

Figure 6

Platform crossing times and the target quadrant time of offspring rats in Morris water maze test.

A: The platform crossing times of the offspring rats from different groups (control group, n= 12; 5 min HIE group, n= 13; 10 min HIE group, n= 12; 15 min HIE group, n= 10) were expressed as mean ± S.D.. a: compared with the control group; b: compared with the 5 min HIE group; c: compared with the 10 min HIE group. The P values were showed in the bracket.

B: The percentage of the time spent in the target quadrant of offspring rats from different groups (control group, n= 12; 5 min HIE group, n= 13; 10 min HIE group, n= 12; 15 min HIE group, n= 10) were expressed as mean ± S.D.. a: compared with the control group; b: compared with the 5 min HIE group; c: compared with the 10 min HIE group. The P values were showed in the bracket.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0082502.g006