Obesity Is Associated with Lower Coronary Microvascular Density
Figure 2
Picrosirius-red staining of collagen, reticulin staining of cardiomyocyte membranes, and CD31 immunostaining of capillaries.
Representative sections of left ventricular biopsies from a non-obese male (BMI: 25 kg/m2) and an obese male (BMI: 39 kg/m2) coronary artery bypass graft surgery patient stained with picrosirius-red demonstrating interstitial and perivascular fibrosis (stained red) and arteriolar dimensions (A, B), reticulin stain demonstrating cardiomyocyte membranes (C, D), and immunostained for CD31 demonstrating capillaries (E, F).