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Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury – Rescue by High-Dose Statin Treatment

Figure 6

I/M Area and I/M Thickness ratio in injured and contralateral carotid arteries.

Atorvastatin significantly reduced I/M Area and I/M Thickness ratio compared to HCD (B-C, E-F, G-H). The degree of stenosis was significantly greater in HCD compared to STATIN pigs (I). *P<0.05.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0080588.g006