Helicase-Like Transcription Factor (Hltf) Regulates G2/M Transition, Wt1/Gata4/Hif-1a Cardiac Transcription Networks, and Collagen Biogenesis
Figure 4
Hltf null hearts (1) and brains (2) share the same defects in the G2/M transition.
Significant decreases (red thermometers = negative effects) in transcript expression of major components of the G2/M transition in Hltf null heart (1) and brain (2) are superimposed on the proprietary multicomponent canonical pathway map from the MetaCore™ database [Straight lines = interactions; Symbols = events; +P = phosphorylation; B = binding; GR = group relation; CS = complex subunit. Colors for lines and symbols are green for positive, and gray for unspecified].