Inhibition of Increased Circulating Tfh Cell by Anti-CD20 Monoclonal Antibody in Patients with Type 1 Diabetes
Figure 6
The expression of IL-21, IL-6 and Bcl-6 from T1D patients before and after treatment (n = 20).
A. The levels of serum IL-21 in pretherapy and posttreatment groups. B. The levels of serum IL-6 in pretherapy and posttreatment groups. C. The levels of IL-21 mRNA in CD4+ T cells were detected by real-time PCR in pretherapy and posttreatment groups. D. The levels of IL-6 mRNA in CD4+ T cells were detected by real-time PCR in pretherapy and posttreatment groups. E. The levels of BCL-6 mRNA in CD4+ T cells were detected by real-time PCR in pretherapy and posttreatment groups. Student's paired t test was performed. *, P<0.05, **, P<0.01, ***, P<0.001.