The Severity of Experimental Autoimmune Cystitis Can be Ameliorated by Anti-CXCL10 Ab Treatment
Figure 2
Histopathological changes in the urinary bladders of chronic EAC mice treated with anti-CXCL10 Ab.
Bladder sections from control or anti-CXCL10 Ab groups are shown at different magnifications (A, C, E, G X30; B, D, F, H X100). Panel F shows sections from EAC-induced mice treated with control Ab to illustrate inflamed bladders characterized by differences in mucosal wall thickness, enlargement of the mucosal layer, and leukocyte infiltration. Panel H shows marked improvement after anti-CXCL10 Ab treatment.