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Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia

Figure 12

Genes expressed differentially in the TG and DRG.

A 65 genes are expressed at least 10-fold higher in the TG than in the DRG. Brain (B), liver (L), olfactory epithelium (OE), and skeletal muscle (SM) were used to visualize the global expression patterns for the selected genes. The expression of genes that are marked with (*) is significantly different between the TG and DRG. Interestingly, 15 of the trigeminally-expressed genes are also expressed in the OE and have a function in olfaction. B In the DRG, many of the 117 specifically expressed genes play a role in the development or regulation of gene expression, such as Ampd1 or Cfd. Of the 117, 23 genes were significantly expressed at higher levels in the DRG than in the TG. In contrast to the TG, we found several Hox genes with higher expression in the DRG than in the TG.

Figure 12

doi: https://doi.org/10.1371/journal.pone.0079523.g012