Comprehensive RNA-Seq Expression Analysis of Sensory Ganglia with a Focus on Ion Channels and GPCRs in Trigeminal Ganglia
Figure 6
Comparison of cumulative FPKM values (sFPKM).
sFPKM values for some prominent ion channels and GPCRs where compared to the sFPKM values of the ORs. The expression of potassium channels is most pronounced in the TG (sFPKM 1551) and DRG (sFPKM 1230), followed by the VGSCs (TG: 963 sFPKM, DRG: 695 sFPKM). Mrgprs, iGlut, P2X, and GABA(A) are expressed at a similar level. Nevertheless, the cumulated FPKM of ORs (TG: 24 sFPKM, DRG: 10 sFPKM) can be compared with the cumulated FPKM of Cnr (TG: 22 sFPKM, DRG: 10 sFPKM), mGlut (TG: 41 sFPKM, DRG: 29 sFPKM), and P2y (TG: 38 sFPKM, DRG: 51 sFPKM). Mrgprs are expressed almost 3-fold higher in the DRG (197 sFPKM) than in the TG (76 sFPKM).