β Oscillation during Slow Wave Sleep and Rapid Eye Movement Sleep in the Electroencephalogram of a Transgenic Mouse Model of Huntington’s Disease
Figure 1
β oscillation in R6/1 Huntington’s disease transgenic mice.
Typical example (9 min 30 sec of recording) of frontal cortical electroencephalogram (A) and hippocampal local field potential (B) and their respective spectrograms (C and D, log scale) in a representative symptomatic R6/1 mouse. Red and blue lines in E represent x and y coordinates of the animal’s position. With the onset of REM sleep (pink band in C, D and F), characterized by immobility and hippocampal θ rhythm (visible in D), the β band (20–35 Hz) clearly visible in the spectrogram for the frontal electrode (C), diminishes in frequency and increases in power as compared to the preceding SWS (blue band in C, D and F), which is characterized by wide 2–8 Hz bands. Different time scales were used for EEGs (A and B, REM sleep) and spectrograms (C and D) for frontal and hippocampal recordings to better illustrate the β oscillation.