A Cross-Platform Comparison of Affymetrix and Agilent Microarrays Reveals Discordant miRNA Expression in Lung Tumors of c-Raf Transgenic Mice
Figure 7
miRNA expression profiling in human lung cancer and c-Raf transgenic mice.
Eight significantly regulated miRNAs identified in c-Raf transgenic mice were compared with the list of 107 miRNAs reported as regulated in human lung cancer studies [39], [48]. Five miRNAs, miR-127, miR-21, miR-146b, miR-183, miR-184 were similarly up-regulated in c-Raf transgenic lung and human lung cancer therefore demonstrating clinical relevance of this particular disease model.