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Hypercholesterolemic Myocardium Is Vulnerable to Ischemia-Reperfusion Injury and Refractory to Sevoflurane-Induced Protection

Figure 5

Effects of GSK3β inhibitor SB216763 on infarct size expressed as a percentage of area at risk in rat hearts exposed to ischemia-reperfusion.

IR: ischemia reperfusion; SB: SB216763; HC: hypercholesterolemia. Data are mean ± SD, n = 8 hearts/group. *P < 0.05 vs. IR; # P < 0.05 vs. HC + IR.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0076652.g005