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Heart Rate Responses to Autonomic Challenges in Obstructive Sleep Apnea

Figure 1

Cold pressor heart rate responses.

A: 37 OSA and 57 control subjects; B: 6 OSA and 20 control female subjects, and 31 OSA and 37 control male subjects. Ai, Bi: Raw heart rate during the complete sequence. Aii, Bii, Biii: Change in heart rate relative to baseline (group mean ± SE), with time-points of significant increase or decrease relative to baseline within-group, and time-points of between-group differences (RMANOVA, p<0.05). Shaded areas indicate challenge periods.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0076631.g001