Sulfamethoxazole Induces a Switch Mechanism in T Cell Receptors Containing TCRVβ20-1, Altering pHLA Recognition
Figure 10
Ramachandran plot of 4 primary residues on CDR2β affected by SMX binding in loop. Plots are for entire trajectory, and show also differences in bound TCR to free TCR. Φ and ψ angles are labeled, axis are from -180 to 180 degrees. Top are with SMX, bottom without. Intensity, right color scale, indicates scaled intensity factor relating percent occupancy across all trajectories, red, highest occupancy scaled to number indicated. All data in each plot represent 100% of angle occupancy summed from all trajectories in set.