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Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation

Figure 5

Cartoon representation of diatom cell biochemistry when acclimated to Fe-limitation.

Not all metabolic pathways are shown. Black and grey pathways and proteins indicate presence during Fe-limitation, white proteins indicate significantly down-regulated proteins, colored pathways were significantly up-regulated in Fe-limited cells compared to Fe-replete cells. A) Pentose Phosphate Pathway, B) The rejoining of the pentose phosphate pathway with glycolysis and generation of pyruvate. C) Polyamine synthesis using spermine synthase. D) Proposed reduction of Fe+3 and eventual transport of Fe into cells. Purple: photosynthesis and glycolysis-gluconeogenesis, red: nucleotide metabolism, teal: lipid metabolism, orange: amino acid metabolism.

Figure 5

doi: https://doi.org/10.1371/journal.pone.0075653.g005