Surface Glycosylation Profiles of Urine Extracellular Vesicles
Figure 5
Unsupervised hierarchical clustering of lectin microarray profiles for intact urine uEVs and purified THP from three healthy individuals.
LM data for all uEV (donors D1, D2, and D3) and THP samples (donors D1, D2 and D4) normalized by rescaling (range 0 to 65200). Individual technical replicates are indicated by designation of 1 to 5. Two groups are evident at 0.28 similarity, three groups at 0.57 similarity. Clustering based on Euclidean distance, complete linkage method. Responses and clustering shown are typical of those obtained from a minimum of 10 healthy uEV enrichment and profiling experiments.