Behavioral and Metabolic Effects of the Atypical Antipsychotic Ziprasidone on the Nematode Caenorhabditis elegans
Figure 4
Caenorhabditis elegans wild-type behavior after Ziprasidone treatment for 24h.
The worms were observed as the pharynx pumping/ min (A) and intervals of defecation cycles (s) (B) on treatment plates. The treatment with Ziprasidone (40 µM) or control (DMSO 0.16% in Acetic acid (1:10 000)) started in L4 larval stage for 24 h (adult). No statistic difference was found compared to control (0.16% DMSO) (mean, SD, n=20). The drug was poured and precipitated on agar plates.