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Deletion of Lipoprotein PG0717 in Porphyromonas gingivalis W83 Reduces Gingipain Activity and Alters Trafficking in and Response by Host Cells

Figure 4

Inflammatory mediator profile of uninfected and P. gingivalis infected HCAEC.

HCAEC were infected with 107 bacteria (MOI of 100). Cell culture supernatants were collected at 24 hours PI and analyzed with Milliplex detection kits. Values represent the mean ± SD concentration from 3 independent experiments (n = 3). **Indicates group means that were significantly different by ANOVA followed by Fisher’s multiple comparison test (P < 0.001).

Figure 4

doi: https://doi.org/10.1371/journal.pone.0074230.g004