SGO1 Maintains Bovine Meiotic and Mitotic Centromeric Cohesions of Sister Chromatids and Directly Affects Embryo Development
Figure 4
Depletion of bovine SGO1 in GV oocytes affected chromosome separation.
A) SGO1 mRNA level after RNAi. Different superscripts indicate a statistical difference (P<0.01). The error bar is expressed as mean ± SEM. B) Chromosome spread after SGO1 RNAi. I: normal metaphase II chromosomes; II, multi-polar chromosome; III and IV, abnormal chromosomal separation, bar = 10 µm; original magnification×1000. C) The percentage of abnormal chromosomes (III and IV) after SGO1-specific interference. Different superscripts indicate a statistical difference (P<0.05). The error bar is expressed as mean ± SEM.