HER2 as a Promising Target for Cytotoxicity T Cells in Human Melanoma Therapy
Figure 1
Expression of HER2 in different human melanoma cells.
(A) Surface expression of HER2 was evaluated by flow cytometry on seven melanoma cell lines (OCM-1, OMM-1, 92-1, Malme-3M, Mel888, SK Mel28 cell, and Mel624) and a primary melanoma (PM) cell. Shaded histograms represent cells stained with Herceptin® and open histograms represent cells stained with a non-related human IgG as control. (B) Western blot analysis showed HER2 protein band (185 kD) in cell lysates of human melanoma cells. β-actin was used as an internal control. A HER2 non-expression cell line K562 was used as a negative control.