Does a Nephron Deficit Exacerbate the Renal and Cardiovascular Effects of Obesity?
Figure 3
24hour urine production, creatinine clearance and 24 hr albumin excretion of wildtype (WT; open bars) and GDNF HET (hatched bars) mice fed control (CONT) or high fat (HFF) diet.
Parameters are expressed in absolute (top panels) values and values adjusted for bodyweight (lower panels). Data analyzed by two way ANOVA with the factors of genotype (gp), diet and interaction (int; diet x genotype). Values are mean ± SEM. n = 7–13 per group.