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Does a Nephron Deficit Exacerbate the Renal and Cardiovascular Effects of Obesity?

Figure 2

Mean arterial pressure (MAP; top panels), heart rate (middle panels) and locomotor activity (bottom panels) for 24hour period (left panels), night time (center) and day time (right panels) in wildtype (WT; open bars) and GDNF HET (hatched bars) mice fed control (CONT) or high fat (HFF) diet.

Data analyzed by two way ANOVA with the factors of genotype (gp), diet and interaction (int; diet x genotype). *P<0.05 using Bonferonni post hoc analysis Values are mean ± SEM. n = WT-CONT 9, -HFF 8; HET-CONT 7, -HFF 5.

Figure 2

doi: https://doi.org/10.1371/journal.pone.0073095.g002