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Unique Association between Global DNA Hypomethylation and Chromosomal Alterations in Human Hepatocellular Carcinoma

Figure 4

Frequencies of allelic imbalance in HCC on each chromosomal arm.

The vertical bars show frequencies of allelic loss (shown in blue) and allelic gain (red); the allelic doses were determined by multiples PCR using a retained allele as a internal control [14]. The red horizontal dotted bar indicates the frequencies of 25%.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0072312.g004