A Meta-Analysis of PTGS1 and PTGS2 Polymorphisms and NSAID Intake on the Risk of Developing Cancer
Figure 4
Forest plot of the association between the PTGS2 rs5275 polymorphism and NSAID use on cancer risk stratified by ethnicity.
The difference in the development of cancer between NSAID users and non-NSAID users homozygous for the major allele (a), between NSAID users and non-NSAID users with minor allele carriers (b), between the non-NSAID users homozygous for the major allele and the minor allele carriers (c), and between the NSAID users homozygous for the major allele and the minor allele carriers (d). Squares represent study-specific ORs; horizontal lines represent 95% CIs; size of square reflects study-specific statistical weight (inverse of the variance); diamonds represent summary OR and 95% CI.