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Bilateral Nerve Alterations in a Unilateral Experimental Neurotrophic Keratopathy Model: A Lateral Conjunctival Approach for Trigeminal Axotomy

Figure 3

Bilateral superficial epitheliopathy (A–B) and gross pictures of the cornea Day 3 (C) and 7 (D) after trigeminal nerve.

Bilateral superficial punctuate keratitis was observed in all cases (A: Axotomized eye, B: its contralateral eye). After trigeminal axotomy, some cases, not all, developed epithelial defect (C), followed by corneal neovascularization (D).

Figure 3

doi: https://doi.org/10.1371/journal.pone.0070908.g003