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Relationship between the Magnitude of Intraocular Pressure during an Episode of Acute Elevation and Retinal Damage Four Weeks later in Rats

Figure 5

ERG component amplitudes recorded during acute IOP elevation vs.

after 4 weeks recovery. Group mean relative amplitude (ratio of treated/fellow control eyes, %, filled symbols, ± SEM) for (A) a-wave (RmP3, P3), (B) b-wave (Vmax, P2), (C) nSTR, (D) nSTR, (E) Photopic b-wave (Vmax, P2) and (F) photopic OP components 4 weeks following acute IOP elevation for each level of IOP (solid curves represent best-fit cumulative normal functions). For comparison, the relative amplitudes of each component recorded during acute IOP elevation are re-plotted from a previous report [20] (unfilled symbols, dashed curves represent best-fit cumulative normal functions).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0070513.g005