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Ron Knockdown and Ron Monoclonal Antibody IMC-RON8 Sensitize Pancreatic Cancer to Histone Deacetylase Inhibitors (HDACi)

Figure 6

Mechanisms underlie IMC-RON8 sensitization of pancreatic cancer cells to Panobinostat.

A) Ron expression after co-treatment of Capan-1, L3.6pl and CFPAC-1 cells with IMC-RON8 and PS. B) Effect of co-treatment of IMC-RON8 and PS on pAkt and PARP cleavage. β-actin was used as a loading control.

Figure 6

doi: https://doi.org/10.1371/journal.pone.0069992.g006