Immunohistochemical, Ultrastructural and Functional Analysis of Axonal Regeneration through Peripheral Nerve Grafts Containing Schwann Cells Expressing BDNF, CNTF or NT3
Figure 6
Examples of longitudinal sections of normal (A), autograft (B) and NT3 graft (C) stained with PanNF (red) and IB4 (green).
(D) Quantification revealed significantly greater numbers of IB4+ axons in normal nerves compared to acellular grafts (*) and in NT3 grafts compared to all other experimental groups (**). (E) The number of CGRP+ axons was not significantly different between experimental groups. Values represent M ± SEM of n = 3; p<0.05. Further details on statistical analysis provided as Statistical Information S1. Scale bar for A–C: 100 µm.