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Improvement in Regional CBF by L-Serine Contributes to Its Neuroprotective Effect in Rats after Focal Cerebral Ischemia

Figure 8

Influence of AOAA on the neuroprotective effect of L-serine in pMCAO rats (six rats per group).

(A) Neurological deficit score. (B) Infarct volume (main effect of different treatments: F1, 23 = 11.74, P = 0.000). (C) Examples of TTC staining after different treatments: a, vehicle; b, L-serine; c, L-serine+AOAA 25 mg/kg; d, L-serine+AOAA 50 mg/kg. **P<0.01, vs. vehicle. L-ser, L-serine.

Figure 8

doi: https://doi.org/10.1371/journal.pone.0067044.g008