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Shotgun Proteomics Identifies Serum Fibronectin as a Candidate Diagnostic Biomarker for Inclusion in Future Multiplex Tests for Ectopic Pregnancy

Figure 5

FN1 and PSG4 ELISA of serum collected at first presentation of women with a PUL, categorized according to final pregnancy outcome: dNVIUP (n = 26); dVIUP (n = 28); dEP (n = 17); NP (n = 11); srPUL (n = 27); pEP (n = 8); and tPUL (n = 3).

ROC curves were generated for ectopic vs non-ectopic patient groups. Analysis was repeated after ambiguous medically treated PUL outcomes (pEP and tPUL) were excluded (-PUL Data).

Figure 5

doi: https://doi.org/10.1371/journal.pone.0066974.g005