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Shotgun Proteomics Identifies Serum Fibronectin as a Candidate Diagnostic Biomarker for Inclusion in Future Multiplex Tests for Ectopic Pregnancy

Figure 1

1D SDS-PAGE of ProteoMinerâ„¢ affinity-purified serum, alongside the original whole sera and flow-through, from women undergoing surgical management of EP (E), surgical management of NVIUP (N) and surgical termination of VIUP (V).

Note the increased complexity and reduction in high abundance proteins in the enriched fractions. Three bands (B1, B2 and B3) appeared differentially expressed and were submitted for PMF.

Figure 1

doi: https://doi.org/10.1371/journal.pone.0066974.g001