A Molecular Predictor Reassesses Classification of Human Grade II/III Gliomas
Figure 2
Incidence on overall survival and comparison of WHO grade II/III versus gene expression-based PAM predictor classification methods.
The WHO classification (dotted lines) and the gene expression-based clusters or predicted classes (solid lines) were compared in a Kaplan-Meier analysis of training (A) and validation (B, C) cohorts. For life expectancy comparison, the Kaplan-Meier curves for overall survival were superimposed for training, validation and mixed cohorts (D, E). A parametric regression model of the overall survival of mixed cohorts was superimposed assuming a Weibull-distributed fit.