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Depth Sensitivity and Source-Detector Separations for Near Infrared Spectroscopy Based on the Colin27 Brain Template

Figure 4

Mean proportion of total sensitivity to the tissue types indicated as a function of source-detector separation.

Errorbars represent standard errors across all nineteen locations in the International 10–20 System. Separate curves represent pre-thresholding of the sensitivity (3-point Green's function) maps at 5, 4, 3, or 2 orders of magnitude (OM) reduction in sensitivity compared to peak, representing progressively less optimal NIRS measurement systems. (A) Sensitivity to brain tissue = gray plus white matter. (B) Non-brain tissue = CSF plus skull plus scalp. (C) Gray matter only. (D) White matter only.

Figure 4

doi: https://doi.org/10.1371/journal.pone.0066319.g004