PPARβ Regulates Liver Regeneration by Modulating Akt and E2f Signaling
Figure 5
Gene expression of key metabolic enzymes involved in glycolysis in wild-type (WT) and PPARβ-null (KO) mice after PH.
(A) Glucose metabolism pathway. Major metabolic enzymes and intermediates are shown. Genes identified by RNA-sequencing and confirmed by quantitative real-time PCR are shaded; the number after each gene name means the ratio of gene expression of WT/KO. Biological pathway analysis was performed by using GenMAPP Pathway (http://www.genmapp.org). Hepatic gene expression levels of (B) Hk2, (C) Gpi1, (D) Pfkl, (E) Adloc, (F) Gapdhs, (G) Pgk1, (H) Pgm1, (I) Eno1, and (J) Pklr in WT and KO mice over a time course from 0 to 72 hours after PH (n = 3). Means ± SD are graphed. * p<0.05.